GeriMedRisk: Understanding QTc Prolongation with Antidepressants and Antipsychotics and Making an Informed Choice for Older Adults.


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Quick Truth Check: Understanding QTc Prolongation with Antidepressants and Antipsychotics and Making an Informed Choice for Older Adults.

• Review fundamentals of cardiac conduction, pathophysiology, risk factors and measurement of QTc prolongation.
• Discuss evidence around individual antidepressants and antipsychotics and their risks of QTc prolongation and subsequent Torsades De Pointes.
• Discuss an evidence-based, pharmacological informed approach to choosing antidepressants and antipsychotics in older adults at risk of Torsades De Pointes.

Saumil Dholakia is a clinical fellow in Geriatric Psychopharmacology and Geriatric Psychiatry at Department of Psychiatry and Behavioral Sciences, McMaster University and GeriMedRisk. Previously, Saumil has worked as a consultant psychiatrist for 10 years with Christian Medical College, Vellore. He is a Bioethicist with a Post-graduate Diploma from Bharathiar University Coimbatore and a Master’s degree from the Joint Center of Bioethics, University of Toronto. His areas of interests are pharmacogenomics in older adults, pharmacologically informed clinical decision-making, deprescribing ethics and MAiD in people with Dementia.


GeriMedRisk-Geriatric Clinical Pharmacology Rounds is a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification program of The Royal College of Physicians and Surgeons of Canada

Post-rounds, please confirm your attendance to receive Royal College CME:

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The Ontario CLRI is funded by the Ministry of Health, and the Ministry of Long-Term Care, and hosted at Baycrest Health Sciences, Bruyère, and the Schlegel-UW Research Institute for Aging.

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